PlainVitamins

Endefen

by Metagenics · powder · 14.81 ounces

  • On the market (NIH)
  • UPC 7 55571 01505 1
  • DSLD label 323351
  • Serving 7.5 g (About 1 Tbsp)
  • 56 servings

Endefen by Metagenics lists 12 ingredients, 12 with an amount per serving of 7.5 g, such as 150 mg of vitamin C, 1 g of apple, powder, 1 g of plantain, powder and 750 mg of arabinogalactans, beside 6 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on February 23, 2025.

What is in Endefen?

Each row as the label prints it, per serving of 7.5 g. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Endefen: Supplement Facts rows against the market (DSLD label 323351, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories30 Calories
Total Fat1 g1%Fat (unspecified) in Endefen against 11,965 products1 g per serving; the middle half of products list 1 g to 2.5 g, the median 1.5 g.1 g

56% of 11,965 products listing fat (unspecified) give more (median 1.5 g).

Total Carbohydrates5 g2%Carbohydrate in Endefen against 21,979 products5 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.5 g

Higher than 65% of 21,979 products listing carbohydrate (median 3 g).

Dietary Fiber2 g7%Fiber in Endefen against 6,987 products2 g per serving; the middle half of products list 1 g to 4 g, the median 2 g.2 g

38% of 6,987 products listing fiber give more (median 2 g).

Total Sugars1 gSugar in Endefen against 11,807 products1 g per serving; the middle half of products list 1 g to 4 g, the median 2 g.1 g

69% of 11,807 products listing sugar give more (median 2 g).

Proteinless than 1 g
Vitamin Cas Calcium Ascorbate150 mg167%Vitamin C in Endefen against 18,583 products150 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg150 mg

Higher than 58% of 18,583 products listing vitamin C (median 100 mg).

Sodium5 mg1%Sodium in Endefen against 14,514 products5 mg per serving; the middle half of products list 15 mg to 142 mg, the median 55 mg.5 mg

89% of 14,514 products listing sodium give more (median 55 mg).

Apple, Powder1 gApple in Endefen against 153 products1,000 mg per serving; the middle half of products list 50 mg to 450 mg, the median 240 mg.1,000 mg

Higher than 90% of 153 products listing apple (median 240 mg).

Plantain, Powder1 g
Arabinogalactansas Larch Gum750 mgArabinogalactan in Endefen against 242 products750 mg per serving; the middle half of products list 50 mg to 1,000 mg, the median 250 mg.750 mg

Higher than 71% of 242 products listing arabinogalactan (median 250 mg).

Soy Lecithin500 mgLecithin in Endefen against 804 products500 mg per serving; the middle half of products list 50 mg to 1,200 mg, the median 200 mg.500 mg

Higher than 59% of 804 products listing lecithin (median 200 mg).

PhosphatidesTypical analysis reveals 115 mg phosphatidylcholine.485 mgPhospholipid in Endefen against 257 products485 mg per serving; the middle half of products list 130 mg to 400 mg, the median 245 mg.485 mg

Higher than 86% of 257 products listing phospholipid (median 245 mg).

Chinese Cinnamon, Powderas Cinnamomum cassia, Powder350 mgCinnamon in Endefen against 601 products350 mg per serving; the middle half of products list 50 mg to 500 mg, the median 200 mg.350 mg

Higher than 65% of 601 products listing cinnamon (median 200 mg).

Green Tea Leaf Extract, Decaffeinatedas CaffeineDecaffeinated, contains no more than 4% caffeine.125 mgGreen Tea in Endefen against 2,595 products125 mg per serving; the middle half of products list 50 mg to 250 mg, the median 100 mg.125 mg

Higher than 55% of 2,595 products listing green tea (median 100 mg).

CatechinsStandardized to 60%75 mgCatechin in Endefen against 108 products75 mg per serving; the middle half of products list 45 mg to 150 mg, the median 85 mg.75 mg

56% of 108 products listing catechin give more (median 85 mg).

Epigallocatechin GallateStandardized to 40%50 mgEGCG in Endefen against 291 products50 mg per serving; the middle half of products list 50 mg to 150 mg, the median 100 mg.50 mg

68% of 291 products listing EGCG give more (median 100 mg).

D-Mannose125 mgMannose in Endefen against 164 products0.125 g per serving; the middle half of products list 0.5 g to 1.5 g, the median 1 g.0.125 g

92% of 164 products listing mannose give more (median 1 g).

Astaxanthin250 mcgAstaxanthin in Endefen against 955 products0.25 mg per serving; the middle half of products list 0.1 mg to 4 mg, the median 1 mg.0.25 mg

67% of 955 products listing astaxanthin give more (median 1 mg).

Source: NIH ODS Dietary Supplement Label Database, label 323351 (entered February 23, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 1,000 mg of apple is higher than 90% of the 153 apple products that print an amount; 7 list more.
  • 92% of the 164 products that print an amount of mannose list more than its 0.125 g of D-mannose (filed by NIH under mannose) (median 1 g).

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Mix about one level tablespoon (7.5 g) in two to four ounces of juice or water once daily, or as directed by your healthcare practitioner.
Warnings
Caution: If pregnant or nursing, or taking medication, consult your healthcare practitioner before use.
Keep out of the reach of children.
Practitioner Exclusive
Allergens and what it does not contain
This product is non-GMO and gluten-free.
Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)
Storage
Storage: Keep tightly closed in a cool, dry place.

Source: label statements in DSLD label 323351.

What else is on the label?

Other ingredients: Rice Bran, Xylitol, Rice Syrup, Solids, Natural Flavors.

How many labels does Endefen have?

4 labels are on file under this name since October 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 323351 (current) Entered February 23, 2025 · on the market · 14.81 ounces · UPC 7 55571 01505 1
  2. Label 216343 Entered March 24, 2020 · off the market February 23, 2024 · 14.81 ounces · UPC 7 55571 01505 1
  3. Label 209494 Entered December 22, 2019 · off the market February 23, 2024 · 14.81 ounces
  4. Label 26799 Entered October 25, 2013 · off the market July 24, 2018 · 14.81 oz. · UPC 7 55571 01505 1

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Metagenics (manufacturer), Gig Harbor, WA. All Metagenics products.

Where next?