DMAE 400 mg

by Signature Supplements · capsule · 100 capsules

  • On the market (NIH)
  • DSLD label 338676
  • Serving 1 to 2 capsules; amounts per 2 capsules
  • 50 servings

DMAE 400 mg by Signature Supplements lists one ingredient: 800 mg of dimethylaminoethanol per serving of 2 capsules. Its current label entered the NIH Dietary Supplement Label Database on August 22, 2025.

What is in DMAE 400 mg?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

DMAE 400 mg: Supplement Facts rows against the market (DSLD label 338676, January 2026 release)
IngredientAmount% DVAmong products listing it
Dimethylaminoethanolas Dimethylaminoethanol Bitartrate 800 mg Not reported Deanol in DMAE 400 mg against 365 products800 mg per serving; the middle half of products list 50 mg to 150 mg, the median 100 mg.800 mg

Higher than over 99% of 365 products listing deanol (median 100 mg).

Not reported: no percentage is available for that row. A missing DSLD percentage does not establish whether an FDA reference value exists.

Source: NIH ODS Dietary Supplement Label Database, label 338676 (entered August 22, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 800 mg of dimethylaminoethanol (filed by NIH under deanol) is higher than over 99% of the 365 deanol products that print an amount; 1 list more.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: For adults, take one (1) to two (2) capsules daily, preferably with a meal.
Warnings
Do not take this product within 2 hours of taking medications or follow the advice of your health care providers. Warning: Pregnant or lactating women should consult a doctor before using any product. Consult doctor before use if you have, or have had, kidney disease, if you are on a magnesium-restricted diet or if you are taking medications or remedies such as those to treat high blood pressure, heart medications, muscle relaxants or diuretics.
Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or low blood pressure.
Not intended for use by persons under the age of 18
Allergens and what it does not contain
No: chemical fillers or binders, artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

Source: label statements in DSLD label 338676.

What else is on the label?

Other ingredients: Cellulose, Diatomaceous Earth.

How many labels does DMAE 400 mg have?

One label is on file, entered on August 22, 2025.

  1. Label 338676 (current) Entered August 22, 2025 · on the market · 100 capsules

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Signature Supplements (distributor), San Clemente, CA. All Signature Supplements products.

Where next?