PlainVitamins

Digestive Enzymes 500 mg

by Dr. Clark Research Association Dr. Clark Zentrum · capsule · 120 capsules

  • On the market (NIH)
  • UPC 7 640116 925038
  • DSLD label 223497
  • Serving 4 capsules
  • 30 servings

Digestive Enzymes 500 mg by Dr. Clark Research Association Dr. Clark Zentrum lists 6 ingredients, 6 with an amount per serving of 4 capsules, such as 410 mg of pepsin, 410 mg of peppermint, 220 mg of lipase and 220 mg of trypsin. Its current label entered the NIH Dietary Supplement Label Database on June 24, 2020.

What is in Digestive Enzymes 500 mg?

Each row as the label prints it, per serving of 4 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Digestive Enzymes 500 mg: Supplement Facts rows against the market (DSLD label 223497, January 2026 release)
IngredientAmount% DVAmong products listing it
Pancreatin410 mg
Pepsin410 mgPepsin in Digestive Enzymes 500 mg against 223 products410 mg per serving; the middle half of products list 25 mg to 130 mg, the median 50 mg.410 mg

Higher than 97% of 223 products listing pepsin (median 50 mg).

Peppermint410 mgPeppermint in Digestive Enzymes 500 mg against 278 products410 mg per serving; the middle half of products list 20 mg to 207.5 mg, the median 50 mg.410 mg

Higher than 83% of 278 products listing peppermint (median 50 mg).

Lipase220 mgLipase in Digestive Enzymes 500 mg against 366 products220 mg per serving; the middle half of products list 5 mg to 25 mg, the median 10 mg.220 mg

Higher than 99% of 366 products listing lipase (median 10 mg).

Trypsin220 mgTrypsin in Digestive Enzymes 500 mg against 77 products220 mg per serving; the middle half of products list 35 mg to 100 mg, the median 75 mg.220 mg

Higher than 99% of 77 products listing trypsin (median 75 mg).

Bromelain220 mgBromelain in Digestive Enzymes 500 mg against 1,337 products220 mg per serving; the middle half of products list 25 mg to 200 mg, the median 50 mg.220 mg

Higher than 79% of 1,337 products listing bromelain (median 50 mg).

Papain110 mgPapain in Digestive Enzymes 500 mg against 607 products110 mg per serving; the middle half of products list 20 mg to 75 mg, the median 40 mg.110 mg

Higher than 86% of 607 products listing papain (median 40 mg).

Source: NIH ODS Dietary Supplement Label Database, label 223497 (entered June 24, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 410 mg of pepsin is higher than 97% of the 223 pepsin products that print an amount; 5 list more.
  • Its 220 mg of lipase is higher than 99% of the 366 lipase products that print an amount; 3 list more.
  • Its 220 mg of trypsin is higher than 99% of the 77 trypsin products that print an amount.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Digestive Enzymes 500 mg's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Adults and children 12 or more years of age: 4 capsules with each meal or as directed.
Warnings
Store out of reach of young children.
Dietary supplements/food supplements should not be used as a substitute for a varied diet. Do not exceed the stated recommended daily dose.
Storage
Store in a dry, cool place.

Source: label statements in DSLD label 223497.

What else is on the label?

Other ingredients: Pancreatin, Pepsin, Peppermint, Lipase, Trypsin, Bromelain, Papain, Hypromellose.

How many labels does Digestive Enzymes 500 mg have?

One label is on file, entered on June 24, 2020.

  1. Label 223497 (current) Entered June 24, 2020 · on the market · 120 capsules · UPC 7 640116 925038

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Dr. Clark Zentrum Limited (distributor), San Gwann, Malta. All Dr. Clark Research Association Dr. Clark Zentrum products.

Where next?