ForestLeaf · Botanical with Nutrients supplement
D-Mannose Defense 1000 mg
9 ingredients on file in the NIH Dietary Supplement Label Database. Currently on-market in the U.S.
- 9
- Ingredients
- 5
- Nutrient categories
- Top 47%
- By ingredient count
D-Mannose Defense 1000 mg is a botanical with nutrients supplement by ForestLeaf in capsule form, listing 9 ingredients in the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. Currently listed as on-market. Daily Value percentages shown below are based on FDA reference daily intake amounts for adults.
Product Details
- Form
- Capsule
- Database Entry Date
- 2022-01-22
- Ingredients
- 9
Supplement Facts (9 Ingredients)
| Ingredient | Group | Amount | % DV |
|---|---|---|---|
| Vitamin C | Vitamin C | Not disclosed on label | No DV |
| D-Mannose | Mannose | Not disclosed on label | No DV |
| Cranberry fruit extract | cranberry | Not disclosed on label | No DV |
| Cranberry | cranberry | Not disclosed on label | No DV |
| Hibiscus | Hibiscus | Not disclosed on label | No DV |
| Hypromellose | Hypromellose | Not disclosed on label | No DV |
| Microcrystalline Cellulose | Cellulose | Not disclosed on label | No DV |
| Vegetable Stearate | Magnesium stearate | Not disclosed on label | No DV |
| Silicon Dioxide | Silicon | Not disclosed on label | No DV |
How does D-Mannose Defense 1000 mg compare?
Ingredients listed on each label, against the botanical with nutrients category average of 16. Data from the NIH DSLD.
D-Mannose Defense 1000 mg lists 15 ingredients fewer than 1 Liver & Organ Quick Detox. That is 7 below the botanical with nutrients average.
What the Label Data Shows
D-Mannose Defense 1000 mg is cataloged in the NIH Dietary Supplement Label Database (DSLD) as a botanical with nutrients supplement built from 9 ingredients from ForestLeaf, sold in capsule form. These ingredients span 5 nutrient categories, botanical, other, vitamin, sugar, and 1 more, reflecting a multi-component formula rather than a single-nutrient product.
Across a broader 9-ingredient formula, 9 of 9 fall outside the FDA's Daily Value system altogether, expected for a broader formula -- the more ingredients a label lists, the more likely it accumulates botanicals, amino acids, or specialty compounds the FDA has never benchmarked.
Market status matters for supplement research. This product is currently listed as on-market in the DSLD, with its label first entered into the database on 2022-01-22. This product is actively distributed in the U.S. right now. As with every DSLD entry, that listing reflects the manufacturer's self-declared label, not an independent safety or efficacy review.
About the DSLD database
The DSLD is a label database, not an FDA approval list, under the 1994 DSHEA framework, dietary supplements do not require pre-market approval, and label information reflects what manufacturers self-declare rather than independent laboratory verification. This page presents factual label data for reference only and is not medical advice; consult a licensed healthcare provider before making decisions about any supplement.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) Supplement label data for D-Mannose Defense 1000 mg: ingredients, % Daily Value, market status, brand · 2026 DSLD captures manufacturer-self-declared label information; the NIH does not verify accuracy or evaluate safety/efficacy. Dietary supplements are regulated under DSHEA 1994, no pre-market FDA approval is required.
Ingredient Breakdown by Category
Daily Value Coverage
Frequently Asked Questions
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Data Sources & Methodology
Data as of 2025. Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD).
Supplement label data sourced from the Source: NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD contains label information from dietary supplement products marketed in the United States.
Daily Value (DV) percentages are based on Source: FDA 21 CFR 101.9 Reference Daily Intake (RDI) values for adults. Products marked "Off Market" may no longer be available for purchase but their label data remains in the database for reference.
Disclaimer, Not Medical Advice
Label data from the Source: NIH Dietary Supplement Label Database (DSLD). This information is for educational and reference purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or combining any dietary supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.
Read our methodology , how this data is sourced, computed, and verified.
Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. This page draws directly on the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.