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ForestLeaf · Botanical with Nutrients supplement

D-Mannose Defense 1000 mg

9 ingredients on file in the NIH Dietary Supplement Label Database, top 47% by ingredient count. Currently on-market in the U.S.

9
Ingredients
Top 47%
By ingredient count
5
Nutrient categories
On Market by ForestLeaf Verify with NIH DSLD → · FDA overview →

D-Mannose Defense 1000 mg is a botanical with nutrients supplement by ForestLeaf in capsule form, listing 9 ingredients in the NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. Currently listed as on-market. Daily Value percentages shown below are based on FDA reference daily intake amounts for adults.

Product Details

Form
Capsule
Database Entry Date
2022-01-22
Ingredients
9

Supplement Facts (9 Ingredients)

Vitamin C
Vitamin C
Amount
Not disclosed on label
% DV
Not reported
D-Mannose
Mannose
Amount
Not disclosed on label
% DV
Not reported
Cranberry fruit extract
cranberry
Amount
Not disclosed on label
% DV
Not reported
Cranberry
cranberry
Amount
Not disclosed on label
% DV
Not reported
Hibiscus
Hibiscus
Amount
Not disclosed on label
% DV
Not reported
Hypromellose
Hypromellose
Amount
Not disclosed on label
% DV
Not reported
Microcrystalline Cellulose
Cellulose
Amount
Not disclosed on label
% DV
Not reported
Vegetable Stearate
Magnesium stearate
Amount
Not disclosed on label
% DV
Not reported
Silicon Dioxide
Silicon
Amount
Not disclosed on label
% DV
Not reported

How does D-Mannose Defense 1000 mg compare?

Ingredients listed on each label, against the botanical with nutrients category average of 16. Data from the NIH DSLD.

D-Mannose Defense 1000 mg9
1 Liver & Organ Quick Detox24
Botanical with Nutrients average16

D-Mannose Defense 1000 mg lists 15 ingredients fewer than 1 Liver & Organ Quick Detox. That is 7 below the botanical with nutrients average.

What the Label Data Shows

According to NIH DSLD label rows, D-Mannose Defense 1000 mg sits in the top 47% of products with a countable formula by declared ingredient count.

D-Mannose Defense 1000 mg is cataloged in the NIH Dietary Supplement Label Database (DSLD) as a botanical with nutrients supplement built from 9 ingredients from ForestLeaf, sold in capsule form. These ingredients span 5 nutrient categories, botanical, other, vitamin, sugar, and 1 more, reflecting a multi-component formula rather than a single-nutrient product.

Across a broader 9-ingredient formula, 9 of 9 lack a percentage Daily Value in the available source record, leaving their regulatory reference status unspecified on this page.

Market status matters for supplement research. This product is currently listed as on-market in the DSLD, with its label first entered into the database on 2022-01-22. This product is actively distributed in the U.S. right now. As with every DSLD entry, that listing reflects the manufacturer's self-declared label, not an independent safety or efficacy review.

About the DSLD database

The DSLD is a label database, not an FDA approval list, under the 1994 DSHEA framework, dietary supplements do not require pre-market approval, and label information reflects what manufacturers self-declare rather than independent laboratory verification. This page presents factual label data for reference only and is not medical advice; consult a licensed healthcare provider before making decisions about any supplement.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD) Supplement label data for D-Mannose Defense 1000 mg: ingredients, % Daily Value, market status, brand · 2026 DSLD captures manufacturer-self-declared label information; the NIH does not verify accuracy or evaluate safety/efficacy. Dietary supplements are regulated under DSHEA 1994, no pre-market FDA approval is required.

Nationwide supplements with similar label profiles

Two DSLD-derived peer sets for D-Mannose Defense 1000 mg, both outside the ForestLeaf brand so the neighborhoods are not catalog containment (the same-type Nearby block above stays type-local).

Similar ingredient count

Nearest cross-brand formulas by declared ingredient count (9 here).

Multi Collagen Protein Unflavoured · HerbTonics 9 ing. Liposomal Iron · Core Med Science 9 ing. Organ Complex · BodyHealth 9 ing. Riboflavin Vitamin B2 400 mg · Nature's Way 9 ing. Hawaiian Astaxanthin · BioAstin 9 ing. Hawaiian Astaxanthin 12 mg · BioAstin 9 ing. Hawaiian Astaxanthin 4 mg · BioAstin 9 ing. Pure Hawaiian Spirulina 3 g · Nutrex Hawaii 9 ing.

Similar Capsule peers

Nearest same-form formulas from other brands.

BloodTonic · HerbTonics 9 ing. Hormonious · Ora 9 ing. 120/80 · Advanced Nutrition by Zahler 9 ing. Super Bee · Foster Regal 9 ing. Mega Acidophilus · Foster Regal 9 ing. C 500 mg & E 250 IU · Wonder Laboratories 9 ing. L-Lysine Defense 1500 mg · Bronson 9 ing. Guggul 250 · Wonder Laboratories 9 ing.

Ingredient Breakdown by Category

botanical
3
Cranberry fruit extract, Cranberry, Hibiscus
other
3
Hypromellose, Microcrystalline Cellulose, Vegetable Stearate
vitamin
1
Vitamin C
sugar
1
D-Mannose
mineral
1
Silicon Dioxide

Daily Value Coverage

0
Above 100% DV
0
Below 100% DV
9
%DV not reported in source

Frequently Asked Questions

What ingredients are in D-Mannose Defense 1000 mg? ▼
D-Mannose Defense 1000 mg contains 9 ingredients. By declared ingredient count it sits in the top 47% of DSLD products PlainVitamins places. Ingredients span 5 categories: botanical, other, vitamin, sugar, mineral.
Who manufactures D-Mannose Defense 1000 mg? ▼
D-Mannose Defense 1000 mg is currently manufactured by ForestLeaf. It is classified as a Botanical with Nutrients supplement in capsule form.
Is D-Mannose Defense 1000 mg still available for purchase? ▼
Yes, D-Mannose Defense 1000 mg is currently listed as on-market in the NIH DSLD database.
What type of supplement is D-Mannose Defense 1000 mg? ▼
D-Mannose Defense 1000 mg is classified as a "Botanical with Nutrients" supplement in the NIH database. This category includes products primarily composed of botanical with nutrients ingredients. Across the full DSLD catalog, products fall into 9 possible categories: Vitamin, Mineral, Botanical, Amino Acid & Protein, Non-Nutrient, Fat & Fatty Acid, Multi-Vitamin & Mineral, Botanical with Nutrients, and Other Combinations.
Data Sources & Methodology

Data as of 2025. Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (DSLD).

Supplement label data sourced from the Source: NIH Dietary Supplement Label Database (DSLD), maintained by the Office of Dietary Supplements at the National Institutes of Health. The DSLD contains label information from dietary supplement products marketed in the United States.

Daily Value (DV) percentages are based on Source: FDA 21 CFR 101.9 Reference Daily Intake (RDI) values for adults. Products marked "Off Market" may no longer be available for purchase but their label data remains in the database for reference.

Disclaimer, Not Medical Advice

Label data from the Source: NIH Dietary Supplement Label Database (DSLD). This information is for educational and reference purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or combining any dietary supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition.

Read our methodology , how this data is sourced, computed, and verified.

Every figure on PlainVitamins is rendered directly from the NIH Dietary Supplement Label Database (DSLD), no number is typed in by an editor. This page draws directly on the NIH DSLD, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.