Circadian Sleep

by Life Extension · capsule · 30 liquid vegetarian capsules

  • On the market (NIH)
  • UPC 7 37870 23003 8
  • DSLD label 232447
  • Serving 1 vegetarian capsule

Circadian Sleep by Life Extension lists 2 ingredients, 2 with an amount per serving of 1 vegetarian capsule, such as 50 mg of nobiletin and 1.5 mg of MicroActive melatonin. Its current label entered the NIH Dietary Supplement Label Database on August 23, 2020.

What is in Circadian Sleep?

Each row as the label prints it, per serving of 1 vegetarian capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Circadian Sleep: Supplement Facts rows against the market (DSLD label 232447, January 2026 release)
IngredientAmount% DVAmong products listing it
Nobiletinas Citrus fruitNobiletin (Form: from young Citrus fruit PlantPart: peel)50 mg
MicroActive Melatoninas Melatonin1.5 mgMelatonin in Circadian Sleep against 1,557 products1.5 mg per serving; the middle half of products list 2 mg to 5 mg, the median 3 mg.1.5 mg

77% of 1,557 products listing melatonin give more (median 3 mg).

Source: NIH ODS Dietary Supplement Label Database, label 232447 (entered August 23, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Circadian Sleep's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Read the entire label and follow the directions carefully prior to use. Directions: Take one (1) capsule daily, before bedtime, or as recommended by a healthcare practitioner. Melatonin is naturally secreted from the pineal gland at night, and should be taken at night for optimal results.
1 Daily
Warnings
Caution: Do not consume alcohol, drive or operate machinery after taking this product.
Warnings: Keep out of reach of children.
Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Allergens and what it does not contain
Non GMO LE Certified
Storage
Store tightly closed in a cool, dry place.

Source: label statements in DSLD label 232447.

What else is on the label?

Other ingredients: Medium Chain Triglycerides, Vegetable Capsule, Microcrystalline Cellulose, Sodium Alginate, Carnuba Wax, Silica.

How many labels does Circadian Sleep have?

2 labels are on file under this name since January 25, 2020: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 232447 (current) Entered August 23, 2020 · on the market · 30 liquid vegetarian capsules · UPC 7 37870 23003 8
  2. Label 210979 Entered January 25, 2020 · off the market July 14, 2020 · 30 liquid vegetarian capsules · UPC 7 37870 23003 8

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Quality Supplements and Vitamins, Inc. (distributor), Ft. Lauderdale, FL. All Life Extension products.

Where next?