Chemical Four

by Chaos and Pain · tablet or pill · 60 tablets

  • On the market (NIH)
  • DSLD label 267070
  • Serving 1 tablet
  • 60 servings

Chemical Four by Chaos and Pain lists 6 ingredients, 4 with an amount per serving of 1 tablet, such as 75 mg of 4-DHEA blend, 150 mg of fadogia agrestis, 150 mg of epicatechin and 50 mg of 6,7 dihydroxybergamottin; 2 sit inside a blend without their own amounts. Its current label entered the NIH Dietary Supplement Label Database on June 16, 2022.

What is in Chemical Four?

Each row as the label prints it, per serving of 1 tablet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Chemical Four: Supplement Facts rows against the market (DSLD label 267070, January 2026 release)
IngredientAmount% DVAmong products listing it
4-DHEA Blend75 mg
4 Androstene-3b-Ol, 17-Onein the blend, no amount given
4 Androstene-3b-ol, 17-one Undecanoatein the blend, no amount given
4 androstene-3b-0l,17-one Caprylatein the blend, no amount given
Fadogia agrestis150 mgFadogia agrestis in Chemical Four against 43 products150 mg per serving; the middle half of products list 325 mg to 1,000 mg, the median 600 mg.150 mg

91% of 43 products listing fadogia agrestis give more (median 600 mg). Per day at the most servings: 300 mg.

Epicatechin150 mgEpicatechin in Chemical Four against 45 products150 mg per serving; the middle half of products list 60 mg to 300 mg, the median 200 mg.150 mg

51% of 45 products listing epicatechin give more (median 200 mg). Per day at the most servings: 300 mg.

6,7 Dihydroxybergamottin50 mg

Source: NIH ODS Dietary Supplement Label Database, label 267070 (entered June 16, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 91% of the 43 products that print an amount of fadogia agrestis list more than its 150 mg of fadogia agrestis (median 600 mg).

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Chemical Four's, rare ingredients counting for more.

  • 4-AndroIronMagLabs 2 shared, 43% alike

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take one (1) tablet in the morning and one (1) tablet in the evening preferably twelve (12) hours apart. Do not exceed two (2) tablets per day. Visit our website for additional information and guidance.
Warnings
Warning: This product is only intended for use by healthy adults over 18 years of age. Do not take this product with any product containing caffeine or other ingredients that have a known stimulant effect. Discontinue use and consult your health care professional if you experience an adverse reaction to this product. Do not exceed recommended serving size or suggested use. Do not use if safety seal is broken or missing.
Consult your physician before using this if you are taking any prescription or over the counter medications or supplements. Do not use this product if you are pregnant, expect to become pregnant or are nursing.
Keep out of reach of children & pets.
Storage
Store in a cool dry place.

Source: label statements in DSLD label 267070.

What else is on the label?

Other ingredients: Microcrystalline, Phosphatidylcholine, Hydroxypropyl-Beta-Cyclodextrin, Phytosterol, Stearic Acid, Magnesium Stearate, Starch, Titanium Dioxide, Silica, FD&C Red #40.

How many labels does Chemical Four have?

One label is on file, entered on June 16, 2022.

  1. Label 267070 (current) Entered June 16, 2022 · on the market · 60 tablets

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Chaos and Pain (manufacturer), Birmingham, AL. All Chaos and Pain products.

Where next?