PlainVitamins

Buffered-Zyme

by Douglas Laboratories · capsule · 90 capsules

  • On the market (NIH)
  • UPC 3 10539 00425 8
  • DSLD label 8094
  • Serving 1 capsule
  • 90 servings

Buffered-Zyme by Douglas Laboratories lists 3 ingredients, 3 with an amount per serving of 1 capsule, such as 39 mg of potassium, 30 mg of pepsin and 50 mg of bromelain, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on April 26, 2012.

What is in Buffered-Zyme?

Each row as the label prints it, per serving of 1 capsule. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Buffered-Zyme: Supplement Facts rows against the market (DSLD label 8094, January 2026 release)
IngredientAmount% DVAmong products listing it
Sodiumas Sodium BicarbonateSodium (Form: from 200 mg Sodium Bicarbonate)55 mg2%Sodium in Buffered-Zyme against 14,514 products55 mg per serving; the middle half of products list 15 mg to 142 mg, the median 55 mg.55 mg

49% of 14,514 products listing sodium give more (median 55 mg).

PotassiumPotassium (Form: from 100 mg Potassium Bicarbonate)39 mg1%Potassium in Buffered-Zyme against 11,614 products39 mg per serving; the middle half of products list 50 mg to 190 mg, the median 99 mg.DV 4,700 mg39 mg

81% of 11,614 products listing potassium give more (median 99 mg).

Pancreatin (4X)100 mg
Pepsin30 mgPepsin in Buffered-Zyme against 223 products30 mg per serving; the middle half of products list 25 mg to 130 mg, the median 50 mg.30 mg

68% of 223 products listing pepsin give more (median 50 mg).

Bromelain50 mgBromelain in Buffered-Zyme against 1,337 products50 mg per serving; the middle half of products list 25 mg to 200 mg, the median 50 mg.50 mg

50% of 1,337 products listing bromelain give more (median 50 mg).

Source: NIH ODS Dietary Supplement Label Database, label 8094 (entered April 26, 2012), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with Buffered-Zyme's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Usage: As a dietary supplement, adults take 1 capsule daily or as directed by your healthcare professional.
Warnings
Tamper resistant package, do not use if outer seal is missing.
KEEP OUT OF REACH OF CHILDREN.
Allergens and what it does not contain
This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sugar, starch, artificial coloring, preservatives or flavoring.
Storage
For optimal storage conditions, store in a cool, dry place. (59°-77°F/15°-25°C) (35-65% relative humidity)

Source: label statements in DSLD label 8094.

What else is on the label?

Other ingredients: Cellulose, Gelatin, Vegetable Stearate.

How many labels does Buffered-Zyme have?

One label is on file, entered on April 26, 2012.

  1. Label 8094 (current) Entered April 26, 2012 · on the market · 90 capsules · UPC 3 10539 00425 8

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Douglas Laboratories (manufacturer), Pittsburgh, PA. All Douglas Laboratories products.

Where next?