PlainVitamins

Berberine Complex

by Integrative Therapeutics · capsule · 90 capsules

  • On the market (NIH)
  • UPC 8 71791 00085 8
  • DSLD label 269867
  • Serving 2 capsules
  • 45 servings

Berberine Complex by Integrative Therapeutics lists 3 ingredients, 3 with an amount per serving of 2 capsules, such as 400 mg of barberry (berberis vulgaris) root extract, 400 mg of oregon grape (berberis aquifolium) root and stem extract and 100 mg of goldenseal (hydrastis canadensis) root and rhizome extract, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on July 21, 2022.

What is in Berberine Complex?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Berberine Complex: Supplement Facts rows against the market (DSLD label 269867, January 2026 release)
IngredientAmount% DVAmong products listing it
Total Carbohydratesless than 1 g1%
Barberry (Berberis vulgaris) root extract400 mgBarberry in Berberine Complex against 138 products400 mg per serving; the middle half of products list 30 mg to 200 mg, the median 75 mg.400 mg

Higher than 80% of 138 products listing barberry (median 75 mg). Per day at the most servings: 1,200 mg.

Oregon Grape (Berberis aquifolium) root and stem extract400 mgOregon Grape in Berberine Complex against 104 products400 mg per serving; the middle half of products list 73.75 mg to 400 mg, the median 150 mg.400 mg

Higher than 74% of 104 products listing oregon grape (median 150 mg). Per day at the most servings: 1,200 mg.

Goldenseal (Hydrastis canadensis) root and rhizome extractas total Alkaloids100 mgGoldenseal in Berberine Complex against 308 products100 mg per serving; the middle half of products list 40 mg to 385 mg, the median 100 mg.100 mg

43% of 308 products listing goldenseal give more (median 100 mg). Per day at the most servings: 300 mg.

Source: NIH ODS Dietary Supplement Label Database, label 269867 (entered July 21, 2022), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

2 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendation: Take 2 capsules three times daily, or as recommended by a healthcare professional.
Warnings
Keep out of reach of children.
Safety sealed with printed inner seal. Do not use if seal is broken or missing.
Warning: Do not use this product if you are pregnant or nursing. If you have diabetes or if you are taking prescription drugs, consult a healthcare professional before use.
Allergens and what it does not contain
Contains no wheat, gluten, soy, dairy, or artificial colors, flavors, or preservatives.
Storage
Keep tightly closed. Store at room temperature. Avoid excessive heat or direct sunlight.

Source: label statements in DSLD label 269867.

What else is on the label?

Other ingredients: plant-derived Capsule, Cellulose, Magnesium Stearate, Silicon Dioxide.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Quality Global Sourcing Bottled & Tested in the USA.

How many labels does Berberine Complex have?

6 labels are on file under this name since July 25, 2013: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 269867 (current) Entered July 21, 2022 · on the market · 90 capsules · UPC 8 71791 00085 8
  2. Label 269619 Entered July 21, 2022 · on the market · 90 capsules · UPC 8 71791 00085 8
  3. Label 223040 Entered June 24, 2020 · on the market · 90 veg capsules · UPC 8 71791 00085 8
  4. Label 184925 Entered April 25, 2019 · off the market January 15, 2020 · 90 veg capsules · UPC 8 71791 00085 8
  5. Label 77788 Entered September 21, 2017 · off the market June 21, 2018 · 90 veg capsules · UPC 8 71791 00085 8
  6. Label 23500 Entered July 25, 2013 · off the market June 21, 2017 · 90 veg capsules · UPC 8 71791 00085 8

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Integrative Therapeutics, LLC (manufacturer), Green Bay, WI. All Integrative Therapeutics products.

Where next?