PlainVitamins

Appe-Curb

by NuMedica · capsule · 240 vegetable capsules

  • On the market (NIH)
  • UPC 8 12527 01054 3
  • DSLD label 323494
  • Serving 4 capsules
  • 60 servings

Appe-Curb by NuMedica lists 7 ingredients, 7 with an amount per serving of 4 capsules, such as 500 mg of vitamin C, 37.5 mg of vitamin B6, 60 mcg of chromium and 1,000 mg of DL-phenylalanine. Its current label entered the NIH Dietary Supplement Label Database on May 21, 2025.

What is in Appe-Curb?

Each row as the label prints it, per serving of 4 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Appe-Curb: Supplement Facts rows against the market (DSLD label 323494, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Cas Ascorbic Acid500 mg556%Vitamin C in Appe-Curb against 18,583 products500 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg500 mg

Higher than 81% of 18,583 products listing vitamin C (median 100 mg). Per day at the most servings: 1,000 mg.

Vitamin B6as Pyridoxine Hydrochloride37.5 mg2,206%Vitamin B6 in Appe-Curb against 15,277 products37.5 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg37.5 mg

Higher than 85% of 15,277 products listing vitamin B6 (median 6 mg). Per day at the most servings: 75 mg.

Chromiumas Chromium Picolinate60 mcg171%Chromium in Appe-Curb against 7,825 products60 mcg per serving; the middle half of products list 45 mcg to 200 mcg, the median 100 mcg.DV 35 mcg60 mcg

61% of 7,825 products listing chromium give more (median 100 mcg). Per day at the most servings: 120 mcg.

DL-Phenylalanine1,000 mgDL-phenylalanine in Appe-Curb against 155 products1,000 mg per serving; the middle half of products list 135 mg to 500 mg, the median 300 mg.1,000 mg

Higher than 95% of 155 products listing DL-phenylalanine (median 300 mg). Per day at the most servings: 2,000 mg.

L-Tyrosine750 mgTyrosine in Appe-Curb against 1,680 products750 mg per serving; the middle half of products list 150 mg to 989 mg, the median 500 mg.750 mg

Higher than 70% of 1,680 products listing tyrosine (median 500 mg). Per day at the most servings: 1,500 mg.

L-Glutamine375 mgGlutamine in Appe-Curb against 1,850 products0.375 g per serving; the middle half of products list 0.356 g to 3 g, the median 1 g.0.375 g

75% of 1,850 products listing glutamine give more (median 1 g). Per day at the most servings: 0.75 g.

5-Hydroxytryptophanas Griffonia simplicifolia Seed Extract75 mg5-HTP in Appe-Curb against 676 products75 mg per serving; the middle half of products list 50 mg to 100 mg, the median 100 mg.75 mg

51% of 676 products listing 5-HTP give more (median 100 mg). Per day at the most servings: 150 mg.

Source: NIH ODS Dietary Supplement Label Database, label 323494 (entered May 21, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 1,000 mg of DL-phenylalanine is higher than 95% of the 155 DL-phenylalanine products that print an amount.

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

2 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: Take four capsules before breakfast and four capsules before lunch or as directed by your healthcare practitioner. Do not take after 3 PM.
Warnings
Caution: Keep out of reach of children.
Allergens and what it does not contain
Does not contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.
GF Gluten free
Storage
Storage: Keep tightly closed in a cool, dry place. Keep away from direct sunlight.

Source: label statements in DSLD label 323494.

What else is on the label?

Other ingredients: Hydroxypropyl Methylcellulose, Magnesium Stearate, Silicon Dioxide.

How many labels does Appe-Curb have?

2 labels are on file under this name since July 25, 2018: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 323494 (current) Entered May 21, 2025 · on the market · 240 vegetable capsules · UPC 8 12527 01054 3
  2. Label 179306 Entered July 25, 2018 · off the market May 30, 2023 · 240 vegetable capsules · UPC 8 12527 01054 3

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names NuMedica LLC (distributor), Tulsa, OK. All NuMedica products.

Where next?