PlainVitamins

Advanced Therapeutics MSM Rx-Wellness

by Natures Plus · tablet or pill · 60 tablets

  • Off the market since February 2022 (NIH)
  • UPC 0 97467 04977 2
  • DSLD label 228364
  • Serving 2 tablets
  • 30 servings

Advanced Therapeutics MSM Rx-Wellness by Natures Plus lists 2 ingredients, 2 with an amount per serving of 2 tablets, such as 60 mg of vitamin C and 2,000 mg of MSM. Its current label entered the NIH Dietary Supplement Label Database on June 24, 2020.

What is in Advanced Therapeutics MSM Rx-Wellness?

Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Advanced Therapeutics MSM Rx-Wellness: Supplement Facts rows against the market (DSLD label 228364, January 2026 release)
IngredientAmount% DVAmong products listing it
Vitamin Cas sulfon-C60 mg100%Vitamin C in Advanced Therapeutics MSM Rx-Wellness against 18,583 products60 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg60 mg

65% of 18,583 products listing vitamin C give more (median 100 mg).

MSM2,000 mgMethylsulfonylmethane in Advanced Therapeutics MSM Rx-Wellness against 1,454 products2,000 mg per serving; the middle half of products list 150 mg to 1,000 mg, the median 500 mg.2,000 mg

Higher than 94% of 1,454 products listing methylsulfonylmethane (median 500 mg).

Source: NIH ODS Dietary Supplement Label Database, label 228364 (entered June 24, 2020), version 9.4.0. See the label on DSLD. Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • Its 2,000 mg of MSM (filed by NIH under methylsulfonylmethane) is higher than 94% of the 1,454 methylsulfonylmethane products that print an amount; 39 list more.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Directions: As a dietary supplement, two tablets with a meal or as recommended by your health care professional.
Warnings
Keep out of reach of children.
This is not a prescription product. It is a dietary supplement made with the highest quality standards.
Allergens and what it does not contain
Gluten free
Free from artificial colors and preservatives.
Storage
Keep tightly closed in a cool, dry place.

Source: label statements in DSLD label 228364.

What else is on the label?

Other ingredients: Di-Calcium Phosphate, Microcrystalline Cellulose, Vegetable Cellulose, Stearic Acid, Magnesium Stearate, Silica, Pharmaceutical Glaze.

How many labels does Advanced Therapeutics MSM Rx-Wellness have?

3 labels are on file under this name since October 1, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 228364 (current) Entered June 24, 2020 · off the market February 28, 2022 · 60 tablets · UPC 0 97467 04977 2
  2. Label 49525 Entered August 25, 2015 · off the market October 31, 2016 · 60 tablets · UPC 0 97467 04977 2
  3. Label 13542 Entered October 1, 2012 · off the market July 31, 2015 · 60 tablets · UPC 0 97467 04977 2

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Natural Organics Laboratories, Inc. makers of Nature's Plus (manufacturer), Amityville, NY. All Natures Plus products.

Where next?