Advanced Digestive Enzymes

by Thorne · capsule · 180 capsules

  • On the market (NIH)
  • UPC 6 93749 40502 3
  • DSLD label 321966
  • Serving 1 to 2 capsules; amounts per 2 capsules
  • 90 servings

Advanced Digestive Enzymes by Thorne lists 4 ingredients, 4 with an amount per serving of 2 capsules, such as 480 mg of betaine hydrochloride, 480 mg of L-glutamic acid hydrochloride, 80 mg of ox bile concentrate and 70 mg of pepsin. Its current label entered the NIH Dietary Supplement Label Database on November 22, 2024.

What is in Advanced Digestive Enzymes?

Each row as the label prints it, per serving of 2 capsules. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

Advanced Digestive Enzymes: Supplement Facts rows against the market (DSLD label 321966, January 2026 release)
IngredientAmount% DVAmong products listing it
Betaine Hydrochloride480 mgBetaine Hydrochloride in Advanced Digestive Enzymes against 914 products480 mg per serving; the middle half of products list 25 mg to 178 mg, the median 50 mg.480 mg

Higher than 88% of 914 products listing betaine hydrochloride (median 50 mg).

L-Glutamic Acid Hydrochloride480 mgGlutamic Acid in Advanced Digestive Enzymes against 697 products480 mg per serving; the middle half of products list 25 mg to 364 mg, the median 80 mg.480 mg

Higher than 77% of 697 products listing glutamic acid (median 80 mg).

Pancreatinas PorcinePancreatin (Form: Porcine) Note: The Pancreatin in one capsule contains no less than: Amylase 15,750 USP Units, Protease 14,000 USP Units, Lipase 2,450 USP Units.140 mg
Ox Bile concentrate80 mgBile in Advanced Digestive Enzymes against 160 products80 mg per serving; the middle half of products list 50 mg to 129.25 mg, the median 100 mg.80 mg

58% of 160 products listing bile give more (median 100 mg).

Pepsinas Porcine70 mgPepsin in Advanced Digestive Enzymes against 223 products70 mg per serving; the middle half of products list 25 mg to 130 mg, the median 50 mg.70 mg

Higher than 59% of 223 products listing pepsin (median 50 mg).

Source: NIH ODS Dietary Supplement Label Database, label 321966 (entered November 22, 2024), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records one serving a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

4 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested use: Take 1-2 capsules with each meal or as recommended by your health-care practitioner.
Warnings
Tamper evident: Use only if bottle is sealed.
If pregnant, consult your health-care practitioner before using this product.
Do not take this product out of the capsule. This product is contraindicated in patients with peptic ulcers.
Allergens and what it does not contain
Gluten free
Storage
Store tightly sealed in a cool, dry place.

Source: label statements in DSLD label 321966.

What else is on the label?

Other ingredients: Hypromellose, Calcium Laurate, Leucine.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Manufactured in the USA using US & imported ingredients.

How many labels does Advanced Digestive Enzymes have?

2 labels are on file under this name since October 24, 2023: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 321966 (current) Entered November 22, 2024 · on the market · 180 capsules · UPC 6 93749 40502 3
  2. Label 298059 Entered October 24, 2023 · off the market February 20, 2024 · 180 capsules · UPC 6 93749 40502 3

DSLD also links this label to: Fem Dophilus (package size difference, same product), Bio-Gest (image difference, same product), Fem Dophilus (package size difference, same product), Fem Dophilus (package size difference, same product), Women's Fem Dophilus (package size difference, same product), Women's Fem Dophilus (image difference, same product), Bio-Gest (image difference, same product), Women's Fem Dophilus (image difference, same product).

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Thorne Research, Inc. (manufacturer). All Thorne products.

Where next?