PlainVitamins

5-HTP 5-Hydroxytryptophan 50 mg

by Natural Factors Stress-Relax · other (e.g. tea bag) · 60 time release caplets

  • On the market (NIH)
  • UPC 0 68958 02826 2
  • DSLD label 282150
  • Serving 1 caplet
  • 60 servings

5-HTP 5-Hydroxytryptophan 50 mg by Natural Factors Stress-Relax lists 2 ingredients, 2 with an amount per serving of 1 caplet, such as 35 mg of calcium and 50 mg of 5-hydroxytryptophan. Its current label entered the NIH Dietary Supplement Label Database on May 24, 2023.

What is in 5-HTP 5-Hydroxytryptophan 50 mg?

Each row as the label prints it, per serving of 1 caplet. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

5-HTP 5-Hydroxytryptophan 50 mg: Supplement Facts rows against the market (DSLD label 282150, January 2026 release)
IngredientAmount% DVAmong products listing it
Calciumas Dicalcium Phosphate35 mg3%Calcium in 5-HTP 5-Hydroxytryptophan 50 mg against 17,831 products35 mg per serving; the middle half of products list 50 mg to 252 mg, the median 115 mg.DV 1,300 mgUL 2,500 mg35 mg

82% of 17,831 products listing calcium give more (median 115 mg). Per day at the most servings: 105 mg.

5-Hydroxytryptophanas Griffonia simplicifolia50 mg5-HTP in 5-HTP 5-Hydroxytryptophan 50 mg against 676 products50 mg per serving; the middle half of products list 50 mg to 100 mg, the median 100 mg.50 mg

55% of 676 products listing 5-HTP give more (median 100 mg). Per day at the most servings: 150 mg.

Source: NIH ODS Dietary Supplement Label Database, label 282150 (entered May 24, 2023), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 2 to 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

6 products list the very same ingredients; the nearest amounts come first.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Suggested Usage: 1 caplet 2-3 times per day with meals or as directed by a health professional. To minimize the risk of gastrointestinal side effects, slowly increase dose over a period of 2 weeks.
Warnings
Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication or supplements with serotonergic activity (specifically those with SSRIs, MOAs or depressant/sedative affect), have a medical condition, or anticipate a surgery.
Keep out of the reach of children.
Sealed for your protection. Do not use if seal is broken.
Allergens and what it does not contain
Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.
Storage
For freshness, store in a cool, dry place.

Source: label statements in DSLD label 282150.

What else is on the label?

Other ingredients: Microcrystalline Cellulose, Carbohydrate Gum, Glycerin, Magnesium Stearate.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): ISURA Non-GMO - Mass spec Documentation - Lab tested; Purity & potency guaranteed.

How many labels does 5-HTP 5-Hydroxytryptophan 50 mg have?

4 labels are on file under this name since June 1, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 282150 (current) Entered May 24, 2023 · on the market · 60 time release caplets · UPC 0 68958 02826 2
  2. Label 75837 Entered August 22, 2017 · off the market February 10, 2022 · 60 enteric coated caplets · UPC 0 68958 02826 2
  3. Label 51652 Entered October 22, 2015 · off the market May 6, 2017 · 60 enteric coated caplets · UPC 0 68958 02826 2
  4. Label 8887 Entered June 1, 2012 · off the market September 16, 2015 · 60 enteric coated caplets · UPC 0 68958 02826 2

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Natural Factors Canada (manufacturer). All Natural Factors Stress-Relax products.

Where next?