PlainVitamins

5-Htp

by Nature's Way · tablet or pill · 60 tablets

  • On the market (NIH)
  • UPC 0 33674 45250 9
  • DSLD label 332135
  • Serving 1 to 2 tablets; amounts per 2 tablets
  • 30 servings

5-Htp by Nature's Way lists 3 ingredients, 3 with an amount per serving of 2 tablets, such as 120 mg of vitamin C, 8 mg of vitamin B6 and 100 mg of L-5-hydroxytryptophan, beside 1 Nutrition Facts row (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on May 21, 2025.

What is in 5-Htp?

Each row as the label prints it, per serving of 2 tablets. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

5-Htp: Supplement Facts rows against the market (DSLD label 332135, January 2026 release)
IngredientAmount% DVAmong products listing it
Total Carbohydratesless than 1 g1%
Vitamin Cas Ascorbic Acid120 mg133%Vitamin C in 5-HTP against 18,583 products120 mg per serving; the middle half of products list 60 mg to 270 mg, the median 100 mg.DV 90 mgUL 2,000 mg120 mg

Higher than 51% of 18,583 products listing vitamin C (median 100 mg). Per day at the most servings: 360 mg.

Vitamin B6as Pyridoxine Hydrochloride8 mg471%Vitamin B6 in 5-HTP against 15,277 products8 mg per serving; the middle half of products list 2 mg to 20 mg, the median 6 mg.DV 1.7 mgUL 100 mg8 mg

Higher than 53% of 15,277 products listing vitamin B6 (median 6 mg). Per day at the most servings: 24 mg.

L-5-Hydroxytryptophanas Griffonia simplicifolia Seed Extract100 mg5-HTP in 5-HTP against 676 products100 mg per serving; the middle half of products list 50 mg to 100 mg, the median 100 mg.100 mg

18% of 676 products listing 5-HTP give more (median 100 mg). Per day at the most servings: 300 mg.

Source: NIH ODS Dietary Supplement Label Database, label 332135 (entered May 21, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

Every amount on this label with a position sits within the middle 80% of the products that list the same ingredient.

The NIH database records 3 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

Which products have the closest formulas?

The products whose ingredient lists overlap most with 5-Htp's, rare ingredients counting for more.

Source: ingredient lists of every product's current label in DSLD (version 9.4.0); similarity weights each shared ingredient by how rare it is.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Recommendation: Adults take 1-2 tablets three times daily with meals, or as recommended by a healthcare professional.
Warnings
Warning: Do not take this product if you are under 12 years of age, or if you are pregnant or nursing.
Warning: Do not take this product if you are under 12 years of age, or if you are pregnant or nursing. Do not take this product if you have or are taking medication for epilepsy, scleroderma, or Parkinson's disease, or if you are taking anti-depressants. If you are taking any medications, consult a healthcare professional before use.
If you suffer from gastrointestinal (GI) disorders such as ulcers, irritable bowel syndrome, Crohn's disease, ulcerative colitis, or celiac disease, you should not use 5-HTP. Some individuals may experience gastrointestinal (GI) upset including abdominal cramping, nausea, or diarrhea while taking this product. If discomfort persists, discontinue use. This product may cause drowsiness; do not drive or operate heavy machinery while taking this product.
Keep out of reach of children.
Safety sealed with inner seal. Do not use if seal is broken or missing.
Allergens and what it does not contain
Vegan Gelatin Free
Gluten free. No wheat, soy, dairy, gelatin, or artificial colors.
Storage
Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Source: label statements in DSLD label 332135.

What else is on the label?

Other ingredients: Cellulose, Maltodextrin, Sodium Croscarmellose, Stearic Acid, Silica, Ethylcellulose, Sodium Alginate, Medium Chain Triglyceride, Oleic Acid.

How many labels does 5-Htp have?

12 labels are on file under this name since August 24, 2012: other sizes, label designs and reformulations. The current one leads this page.

  1. Label 332135 (current) Entered May 21, 2025 · on the market · 60 tablets · UPC 0 33674 45250 9
  2. Label 327852 Entered February 23, 2025 · on the market · 30 tablets · UPC 0 33674 45240 0
  3. Label 204314 Entered June 24, 2019 · off the market January 25, 2021 · 60 tablets · UPC 0 33674 45250 9
  4. Label 204313 Entered June 24, 2019 · off the market December 20, 2024 · 30 tablets · UPC 0 33674 45240 0
  5. Label 79914 Entered October 21, 2017 · off the market October 5, 2018 · 60 tablets · UPC 0 33674 45250 9
  6. Label 79907 Entered October 21, 2017 · off the market October 5, 2018 · 30 tablets · UPC 0 33674 45240 0
  7. Label 57999 Entered March 24, 2016 · off the market February 15, 2017 · 60 tablets · UPC 0 33674 45250 9
  8. Label 54687 Entered December 23, 2015 · off the market February 15, 2017 · 30 tablets · UPC 0 33674 45240 0
  9. Label 40536 Entered December 29, 2014 · off the market February 25, 2016 · 60 tablets · UPC 0 33674 45250 9
  10. Label 40532 Entered December 29, 2014 · off the market November 9, 2015 · 30 tablets · UPC 0 33674 45240 0
  11. Label 12336 Entered August 24, 2012 · off the market December 5, 2014 · 30 tablets · UPC 0 33674 45240 0
  12. Label 12320 Entered August 24, 2012 · off the market December 5, 2014 · 60 tablets · UPC 0 33674 45250 9

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Nature's Way Brands, LLC (manufacturer), Green Bay, WI. All Nature's Way products.

Where next?