PlainVitamins

2-in-1 Cleanse & Flush

by Irwin Naturals · softgel capsule · 60 liquid softgels

  • On the market (NIH)
  • UPC 7 10363 59711 5
  • DSLD label 323273
  • Serving 2 liquid soft-gels
  • 30 servings

2-in-1 Cleanse & Flush by Irwin Naturals lists 13 ingredients, 11 with an amount per serving of 2 liquid soft-gels, such as 100 mcg of chromium, 1,100 mg of extra virgin olive oil, 222.5 mg of milk thistle seed extract and 200 mg of cascara sagrada bark extract; 2 sit inside a blend without their own amounts, beside 3 Nutrition Facts rows (calories, fat and the like). Its current label entered the NIH Dietary Supplement Label Database on January 23, 2025.

What is in 2-in-1 Cleanse & Flush?

Each row as the label prints it, per serving of 2 liquid soft-gels. The capsule beside an amount places it among every product in the NIH database that lists the same ingredient: the bar is the middle half of their amounts, the line in it the median, the whiskers the 10th and 90th percentiles; the green tick is the FDA Daily Value and the red dashed tick the adult upper limit (IOM).

2-in-1 Cleanse & Flush: Supplement Facts rows against the market (DSLD label 323273, January 2026 release)
IngredientAmount% DVAmong products listing it
Calories20 Calories
Total Fat1 g1%Fat (unspecified) in 2-in-1 Cleanse & Flush against 11,965 products1 g per serving; the middle half of products list 1 g to 2.5 g, the median 1.5 g.1 g

56% of 11,965 products listing fat (unspecified) give more (median 1.5 g). Per day at the most servings: 2 g.

Total Carbohydrates1 g1%Carbohydrate in 2-in-1 Cleanse & Flush against 21,979 products1 g per serving; the middle half of products list 1 g to 6 g, the median 3 g.1 g

74% of 21,979 products listing carbohydrate give more (median 3 g). Per day at the most servings: 2 g.

Protein1 gProtein in 2-in-1 Cleanse & Flush against 8,985 products1 g per serving; the middle half of products list 2 g to 24 g, the median 16 g.1 g

77% of 8,985 products listing protein give more (median 16 g). Per day at the most servings: 2 g.

Chromiumas Chromium Picolinate100 mcg286%Chromium in 2-in-1 Cleanse & Flush against 7,825 products100 mcg per serving; the middle half of products list 45 mcg to 200 mcg, the median 100 mcg.DV 35 mcg100 mcg

47% of 7,825 products listing chromium give more (median 100 mcg). Per day at the most servings: 200 mcg.

Extra Virgin Olive Oil1,100 mgOlive Oil in 2-in-1 Cleanse & Flush against 70 products1,100 mg per serving; the middle half of products list 200 mg to 1,200 mg, the median 500 mg.1,100 mg

Higher than 70% of 70 products listing olive oil (median 500 mg). Per day at the most servings: 2,200 mg.

Milk Thistle Seed Extract222.5 mgMilk Thistle in 2-in-1 Cleanse & Flush against 1,277 products222.5 mg per serving; the middle half of products list 90 mg to 300 mg, the median 175 mg.222.5 mg

Higher than 60% of 1,277 products listing milk thistle (median 175 mg). Per day at the most servings: 445 mg.

Cascara Sagrada Bark Extract200 mgCascara Sagrada in 2-in-1 Cleanse & Flush against 240 products200 mg per serving; the middle half of products list 100 mg to 431.25 mg, the median 175 mg.200 mg

Higher than 53% of 240 products listing cascara sagrada (median 175 mg). Per day at the most servings: 400 mg.

Cinnamon Bark Extractas Cinnamomum zeylanicum Bark Extract5:1100 mgCinnamon in 2-in-1 Cleanse & Flush against 601 products100 mg per serving; the middle half of products list 50 mg to 500 mg, the median 200 mg.100 mg

60% of 601 products listing cinnamon give more (median 200 mg). Per day at the most servings: 200 mg.

Gymnema leaf extract20:167.5 mgGymnema in 2-in-1 Cleanse & Flush against 444 products67.5 mg per serving; the middle half of products list 67 mg to 323.33 mg, the median 200 mg.67.5 mg

74% of 444 products listing gymnema give more (median 200 mg). Per day at the most servings: 135 mg.

Cardamom Fruit Extract4:150 mgCardamom in 2-in-1 Cleanse & Flush against 43 products50 mg per serving; the middle half of products list 88.65 mg to 1,078 mg, the median 970 mg.50 mg

86% of 43 products listing cardamom give more (median 970 mg). Per day at the most servings: 100 mg.

Lemon Balm Aerial Extract10:150 mgLemon balm in 2-in-1 Cleanse & Flush against 475 products50 mg per serving; the middle half of products list 50 mg to 200 mg, the median 100 mg.50 mg

65% of 475 products listing lemon balm give more (median 100 mg). Per day at the most servings: 100 mg.

Marshmallow Root Extract10:150 mgMarshmallow in 2-in-1 Cleanse & Flush against 290 products50 mg per serving; the middle half of products list 50 mg to 224 mg, the median 100 mg.50 mg

72% of 290 products listing marshmallow give more (median 100 mg). Per day at the most servings: 100 mg.

Turmeric Root Extract50 mgTurmeric in 2-in-1 Cleanse & Flush against 2,369 products50 mg per serving; the middle half of products list 50 mg to 500 mg, the median 150 mg.50 mg

71% of 2,369 products listing turmeric give more (median 150 mg). Per day at the most servings: 100 mg.

Curcuminoids95%47.5 mgCurcuminoid in 2-in-1 Cleanse & Flush against 309 products47.5 mg per serving; the middle half of products list 40 mg to 300 mg, the median 100 mg.47.5 mg

69% of 309 products listing curcuminoid give more (median 100 mg). Per day at the most servings: 95 mg.

BioPerine Complex3 mg
BioPerineas Black Pepper Fruit Extract95% piperinein the blend, no amount given
Ginger Rhizome Extractas Gingerols5% gingerolsin the blend, no amount given

Source: NIH ODS Dietary Supplement Label Database, label 323273 (entered January 23, 2025), version 9.4.0. See the label on DSLD or its label image (PDF). Amounts are what the maker printed; DSLD does not test products. Daily Values: the FDA's Daily Value page.

Is that a lot?

The rows in the top or bottom tenth of the products that list the same ingredient, and any above the adult upper limit at the most servings a day the directions give:

  • 86% of the 43 products that print an amount of cardamom list more than its 50 mg of cardamom (median 970 mg).

The NIH database records 2 servings a day from the label's directions; its % Daily Values are for adults and children 4 or more years of age. The directions as printed are further down this page.

The Tolerable Upper Intake Level is the most of a nutrient per day, from food, water and supplements together, that is likely to pose no risk for almost all adults (Institute of Medicine, 2011). It does not apply under medical supervision. This page compares labels; it is not medical advice.

Sources: amounts from the DSLD label; Daily Values from 21 CFR 101.9(c)(8)(iv); adult upper limits from the Institute of Medicine's DRI summary tables (2011). How positions are computed.

What does the label say about taking it?

Quoted from the label as DSLD transcribed it: the maker's words, including any claim about what the product does, which the FDA has not evaluated and PlainVitamins does not endorse.

Directions
Dictions: Take two (2) liquid soft-gels in the morning prior to breakfast and two (2) liquid soft-gels in the evening, prior to bedtime. Drink a full glass (8oz) of water with each serving. Do not exceed four (4) liquid soft-gels per day. If stools are loose, reduce intake to three (3) liquid soft-gels per day.
Warnings
Usage warnings: Do not use if safety seal is broken. Do not use if you have an intestinal obstruction, bile duct obstruction, hemorrhoids or other intestinal disorders. Do not use if you are taking any other product concurrently that has laxative effects. Do not exceed recommended daily intake. Note: This product is not intended to be used without breaks. Cascara Sagrada belongs to a family of plants containing compounds with laxative effects. Can lead to dehydration and electrolyte loss. With long-term use without breaks, these ingredients may interfere with diagnostic imaging procedures of the colon. Taking a break of 30 or more days between use cycles will help maintain natural regularity. Not intended for long-term use.
Check with your doctor before using this product if you are using medication, including diuretics, heart medications, and corticosteroids, or have any medical conditions, including but not limited to diabetes or blood sugar disorders. Do not use if you may become pregnant, are pregnant or nursing.
Not intended for use by persons under 18. Keep out of reach of children.
Notice: This product contains Cascara Sagrada. Read and follow the directions carefully. Do not use if you have or develop diarrhea, loose stools, or abdominal pain because Cascara Sagrada may worsen these conditions and be harmful to your health.
Consult your physician if you have frequent diarrhea or if you are pregnant, nursing, taking medication, or have a medical condition.
Contains: Soy
Allergens and what it does not contain
No preservatives added.
Storage
Store in a cool, dry place.

Source: label statements in DSLD label 323273.

What else is on the label?

Other ingredients: Gelatin, Water, Purified, Glycerin, Beeswax, Dextrin, Soy Lecithin, Turmeric, Maltodextrin, Titanium Dioxide, Riboflavin, Silicon Dioxide, Sodium Copper Chlorophyllin.

Seals and symbols as the label prints them (the maker's; a certifier's own list confirms a seal): Pass Quality Tested Guaranteed.

How many labels does 2-in-1 Cleanse & Flush have?

One label is on file, entered on January 23, 2025.

  1. Label 323273 (current) Entered January 23, 2025 · on the market · 60 liquid softgels · UPC 7 10363 59711 5

Source: DSLD label entry and market events, version 9.4.0 (labels entered through September 25, 2025).

Who makes it?

The label names Irwin Naturals (manufacturer, distributor), Los Angeles, CA. All Irwin Naturals products.

Where next?