Comparison
Methyl Folate and L-5-MTHF Natural S-Isomer
Methyl Folate (NuMedica) lists 2 distinct ingredients and L-5-MTHF Natural S-Isomer (Designs for Health) 2 (rows of one ingredient counted once); 2 are on both labels. On the site's similarity measure, which compares ingredient lists (1 for the same list, rarer ingredients counting for more; amounts are not part of it), the two formulas score 1.00: the same ingredients, at the amounts in the table below.
| Ingredient | Methyl Folate | L-5-MTHF Natural S-Isomer |
|---|---|---|
| Folate | 1,360 mcg DFE (340%) | 1,000 mcg |
| 5-methyltetrahydrofolate glucosamine | 1,482 mcg | 2,000 mcg |
Amounts are per serving as DSLD gives them: Methyl Folate, 1 capsule; L-5-MTHF Natural S-Isomer, 1 capsule. Current labels entered April 2025 and July 2013. Percentages of the Daily Value from 21 CFR 101.9. Source: NIH ODS Dietary Supplement Label Database.
Each product on its own
- Methyl FolateNuMedica: every row against all products listing it
- L-5-MTHF Natural S-IsomerDesigns for Health: every row against all products listing it